Urea derivatives as inhibitors of IMPDH enzyme

专利名称：Urea derivatives as inhibitors of IMPDH

enzyme

发明人：DAVID M ARMISTEAD,MICHAEL C.

BADIA,GUY W BEMIS,RANDY S.

BETHIEL,CATHARINE A. FRANK,PERRY M.NOVAK,STEVEN M. RONKIN,JEFFREY O.SAUNDERS

申请号：AU2678597申请日：19970421公开号：AU723730B2公开日：20000907

摘要：The present invention relates to a novel class of compounds which are IMPDHinhibitors. This invention also relates to pharmaceutical compositions comprising thesecompounds. The compounds and pharmaceutical compositions of this invention areparticularly well suited for inhibiting IMPDH enzyme activity and consequently, may beadvantageously used as therapeutic agents for IMPDH mediated processes. Thisinvention also relates to methods for inhibiting the activity of IMPDH using thecompounds of this invention and related compounds.

申请人：VERTEX PHARMACEUTICALS INCORPORATED

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