IMPROVED MUTANTS OF (2,5-DKG) REDUCTASE

专利名称：IMPROVED MUTANTS OF (2,5-DKG)

REDUCTASE

发明人：POWERS, David, B.,ANDERSON, Stephen申请号：EP97902830.0申请日：19970109公开号：EP0873411A1公开日：19981028

摘要：Mutants of 2,5-diketo-D-gluconic acid reductase A an enzyme used to produce2-keto-L-gluconic acid, a precursor of ascorbic acid (vitamin C), are prepared by site-directed mutagenesis. These mutants may exhibit one or more of the followingcharacteristics: improved temperature stability, increased resistance to substrateinhibition, increased turnover of the substrate by the enzyme and increased affinity forthe substrate.

申请人：RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

地址：ASB Annex II, Bevier Road, P.O. Box 1179 Piscataway, NJ 08855-1179 US

国籍：US

代理机构：Goldin, Douglas Michael

更多信息请下载全文后查看